Natural State Labs currently offers hereditary cancer screening and toxicology testing, with plans to expand the molecular offerings. With a repuation for excellent customer service, accuracy and a quick turnaround time. NSL seeks to facilitate higher-quality outcomes for patients.
As technology and scientific research push molecular and genetic capabilities, we are discovering how critical each of the over 6 million components to every individual’s genetic code are. Genetic testing facilitates opportunities to identify mutations and deletions of genes and allow people to reduce their risk of disease and detect diseases earlier while providing a personalized treatment plan. At Natural State Labs, we specialize in helping clinicians and patients make the most of these individual differences. We have partnered with leading manufacturers of genotyping technologies to identify these unique variations. Our laboratory provides a clinical support team of technicians and scientists who deliver accurate results and bring clarity to this advancing science.
Genetic testing involves examining your DNA, the chemical database that carries instructions for your body's functions.
Predictive Genetic Testing can reduce the stress of the unknown, offering clear and actionable results of your genetic risk to key cancers and diseases.
Genetic testing can reveal changes (mutations) in your genes that may cause illness or disease. Catching these mutations early can be key to getting the right treatments (if required).
The obvious benefit of genetic testing is the chance to better understand of your risk for a certain disease. Testing is not perfect, but it can often help you make decisions about your health.
Genetic testing involves examining your DNA, the database that carries instructions for your body's functions.
Hereditary cancers are believed to be responsible for 10% of all cancers. Hereditary cancer screenings indicate genetic risk to key cancers and diseases.
Here at NSL, we use cutting edge technology with NextSeq 550.
Ideal patients have at least one of the following:
- 3 or more first-degree relatives (mother, father, sisters, brothers, children) with any of the top 6 cancers that are affiliated with BRCA 1 & 2 (breast, ovarian, uterine, prostate, pancreatic, and colorectal)
- 3 or more relatives on one side of his/her family who have had the same type of cancer
- A cluster of cancers in his/her family that are known to be linked to a single gene mutation (such as breast, ovarian and pancreatic cancers)
- A known genetic mutation in one or more family members who have already had genetic testing
- A personal history of cancer
- Hereditary Cancer Test Result Possibilities
Negative: The patient does not have genetic variations that indicate that he/she is at increased risk of developing cancer.
VUS (Variant of Unspecified Significance): The patient does have genetic variations, but these variations do not indicate that he/she is at increased risk of developing cancer.
Positive: The patient does have genetic variations which indicate that he/she is at increased risk of developing cancer.
*Results are not a guarantee that a patient will or will not receive a diagnosis of cancer.
We believe that the future of cancer isn’t in how we treat it, but in how quickly we are aware of the presence and make-up of the cancer. Hereditary cancer is believed to be responsible for 10% of all diagnosed cancers; our non-invasive hereditary cancer screening can let you know if you are genetically predisposed to certain hereditary cancers. The process is a simple buccal swab provided by us, followed by next generation sequencing, an advanced technology that lets us to look at multiple strands of your DNA at the same time. While this test cannot definitively tell you if you will or will not get cancer, it does allow you and your health care provider to create a proactive plan for your future.
Natural State Laboratories is the only independent lab of its kind in the state of Arkansas that is using this cutting-edge, medical technology. Our Next Generation Sequencing allows parallel sequencing of millions of short pieces of DNA simultaneously using DNA gathered from a non-invasive, buccal swab. The study of cancer genomes has shown that abnormalities in genes drive the development and growth of many types of cancers. These revelations have improved our understanding of the biology of cancer and are guiding new methods of diagnosing and treating the disease. There was a time when patients had to wait to actually get cancer before they could do anything about the cancer, but it is now possible to evaluate an individual’s risk before a single symptom is ever experienced. NSL is proud to partner with a genetic counseling firm that helps patients and their physician decipher the results of their hereditary cancer test and determine prudent next steps.
screening and toxicology testing, with plans to expand the molecular offerings. With a reputation for excellent customer service, accuracy and a quick turnaround time. NSL seeks to facilitate higher-quality outcomes for patients
Patients with the following personal or family history may qualify for Cardiomyopathy:
Benefits of Detection: This panel is for patients who have a personal or family history of Parkinson’s disease, Alzheimer’s disease or dementia. While genetics are not believed to be the sole cause of these diseases, research does show that abnormal changes in genes are a contributing factor with their onset. These genetic changes and abnormalities may be passed down in families. Children, siblings and parents of patients who are determined to have this genetic variation are 50% more likely to also be at increased risk. Detection of gene variations or abnormalities associated with Parkinson’s disease, Alzheimer’s disease and/or dementia does not mean that an individual will develop one of these diseases. Awareness of the potential does allow families the opportunity to plan ahead, make precautionary and predetermined care decisions, participate in research studies, and identify support networks for caregivers and patients.
Warning Signs and Treatments: Abnormal imaging of the brain, memory loss that interferes with daily life and functioning, mood and personality changes, difficulty carrying on conversations, inability to complete familiar tasks, confusion with time and places and problems moving or controlling movement. Although there is currently no cure for Parkinson’s disease, Alzheimer’s disease or dementia, there are treatments and procedures available that have shown success slowing the progression of these diseases and lessening the severity of the patient’s symptoms.
Approximately 1 million Americans are currently living with Parkinson’s disease and 5 million are suffering from Alzheimer’s disease.
Alzheimer’s disease, Parkinson’s disease, and dementia are conditions that affect the brain and spinal cord. Research has shown that these diseases can sometimes be caused by abnormal changes in our genes, and these genetic changes can be inherited and passed down in families. Having a family history of Parkinson’s disease, Alzheimer’s disease, dementia, or a similar condition may increase your risk of having that condition. Genetic testing can help a patient with the planning and decision-making process for treatment of their disease. This panel is for patients who have a personal or family history of Parkinson’s disease, Alzheimer’s disease, or dementia. Some warning signs of these diseases include abnormal imaging of the brain, difficulty moving or controlling one’s movement, memory loss that interferes with daily life, changes in mood or personality, difficulty having a conversation or completing familiar tasks, and confusion with the time or place.
Respiratory Pathogen Panel
Upper respiratory infections are one of the most common reasons for physician visits. These infections can be viral, bacterial, mycoplasia or fungal in their origin. Research shows that while 90-98% of upper respiratory infections are actually viral, 65% of patients seen for a URI are prescribed an antibiotic. NS Genomics offers a quick turnaround time so that patients can receive the treatment they need sooner and, should antibiotics be needed, recommends the most effective antibiotic for the infection detected.
Gastrointestinal infections can be viral, bacterial or parasitic. Most are self-resolving and do not require pharmaceutical intervention. Treating these infections with antibiotics when not necessary or with the wrong antibiotics can exacerbate the situation and create additional medical issues. NS Genomics offers a 31 pathogen panel to identify the correct source of illness and, if needed, the appropriate antibiotics for successful treatment.
50% of nail disorders are bacterial and 50% are fungal. NS Genomics’ panel tests nail and infected adjacent tissue for 29 fungal pathogens and 29 bacterial pathogens. The resulting report guides physicians towards appropriate treatments.
The FH Panel looks at 5 genes associated with familial hypercholesterolemia.
•Patients with a personal and/or family history suggestive of a FH should consider this screening and are considered at risk if there are high cholesterol levels, very high levels of low-density lipoprotein, and cardiovascular disease.
•Patients identified with FH can benefit from increased surveillance and preventative steps to better manage their risks. Medical intervention may include a combination of medication therapy, low-fat diet, exercise, weight control and not smoking. A patient with a positive result may encourage family members to be tested to help define their risk. If a pathogenic variant is identified in your patient, close relatives (children, siblings, parents) could have as high as a 50%risk to also be at increased risk. In some cases, screening should begin in childhood.
Adverse drug reactions are the 4th leading cause of death in America and, according to the FDA, the reason 4.5 million Americans visit their doctor’s office or the ER every year. Pharmacogenomics is the study of your unique genetic makeup and how it influences drug effectiveness in order to personalize a patient’s drug therapy. Currently, medications are prescribed based on a patient’s weight, height, gender, condition, and previous drug history resulting in trial and error. There are many pathways in our body that metabolize drugs and seemingly small genetic variations can contribute to an adverse drug reaction. These risks can be significantly minimized through pharmacogenomic testing. NS Genomics’ testing can identify the way that a patient metabolizes a drug and assist providers in choosing ideal and unique drug combinations.
Genetic profiles contain six enzymes that metabolize 90 percent of all medications patients are given. These genes and enzymes help determine each individual’s rate of metabolism. These profiles can reveal if a patient processes medication too quickly or too slowly; both can cause complications. Research shows that people fall into one of four general metabolizer types:
•Poor metabolizer: Patients who are poor metabolizers experience a very slow breakdown of medications, making side effects more pronounced. That means standard doses of certain medications may not work as intended.
•Intermediate metabolizer: A slowed metabolism may impact breakdown of medications, causing effects similar to poor metabolizers, but not as pronounced.
•Extensive metabolizer: Considered a “normal” rate of metabolism. Patients are likely to metabolize medication normally and medication is likely to work as intended.
•Ultra rapid metabolizer: Patients in this group metabolize medications too quickly to experience relief from symptoms of depression or other disorders.
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